Hackage :: [Package]

RNAFold: RNA secondary structure prediction

[ bioinformatics, gpl, library, program ] [ Propose Tags ]

RNAfold v2 using the ADPfusion library. The RNAfold algorithm is used to determine how fast we can be compared to a highly optimized C program.

If possible, build using the GHC llvm backend, and GHC-7.2.2. GHC-7.4.x produces very bad code on my system, please benchmark using 7.2.2.

NOTE I'd like to rename this package to RNAfold, like the C implementation. Do not install "globally", especially if you normally use RNAfold from the ViennaRNA package, for obvious reasons.

NOTE I am reluctant to call this v2 for now.

[Skip to Readme]
Versions 0.0.2.1, 1.99.1.0, 1.99.1.1, 1.99.1.2, 1.99.1.3, 1.99.3.4
Dependencies ADPfusion (==0.0.1.1), base (==4.*), BiobaseVienna (==0.2.2.4), BiobaseXNA (==0.6.2.4), mtl (>=2), primitive (==0.4.*), PrimitiveArray (==0.2.1.1), strict (>=0.3.2), vector (==0.9.*) [details]
License GPL-3.0-only
Copyright Christian Hoener zu Siederdissen, 2010-2012
Author Christian Hoener zu Siederdissen (Haskell), Ivo L. Hofacker et al (ViennaRNA), 2010-2012
Maintainer choener@tbi.univie.ac.at
Category Bioinformatics
Home page http://www.tbi.univie.ac.at/~choener/adpfusion
Source repo head: git clone git://github.com/choener/RNAfold
Uploaded by ChristianHoener at Sun May 20 16:49:47 UTC 2012
Distributions NixOS:1.99.3.4
Executables RNAFold
Downloads 3101 total (17 in the last 30 days)
Rating (no votes yet) [estimated by rule of succession]
Your Rating
  • λ
  • λ
  • λ
Status Docs uploaded by user
Build status unknown [no reports yet]
Hackage Matrix CI

Modules

[Index]

Flags

NameDescriptionDefaultType
llvm

build using llvm backend

EnabledAutomatic

Use -f <flag> to enable a flag, or -f -<flag> to disable that flag. More info

Downloads

Maintainer's Corner

For package maintainers and hackage trustees

Readme for RNAFold-1.99.1.2

[back to package description]

ViennaRNA RNAfold v2, MFE variant using the ADPfusion library

Introduction

This algorithm is the second, and much larger, test case for ADPfusion. We implement "RNAfold v2" in the MFE variant using "-d2" dangles. Both a library version and an executable are created. The "RNAFold" binary expects single sequences, one per line. Backtracking tracks all co-optimal structures.

Installation

A simple "cabal update && cabal-dev install RNAFold" should be enough.

Runtime notes

Using Haskell and ADPfusion, we come to within x3-x4 for this package. Between the initial test case / submission (in 0.0.0.3) I have traded in some performance improvements for much better readability in BioInf.RNAfold.Energy. The C version of RNAfold employs some other methods to improve performance. Consider:

base -~+ inner-1 +~- base base -~+ inner-2 +~- base

where it is advantageous to calculate the outer basepair only once, not twice as we are doing. It is probably better to try to improve the handling of fusioned code and/or final assembler generation than finding calculations common to different parts of CFG's.