/* prototypes for energy_par.c */ #ifndef VIENNA_RNA_PACKAGE_ENERGY_PAR_H #define VIENNA_RNA_PACKAGE_ENERGY_PAR_H #include #define PUBLIC extern double lxc37; /* parameter for logarithmic loop energy extrapolation */ extern int stack37[NBPAIRS+1][NBPAIRS+1]; extern int stackdH[NBPAIRS+1][NBPAIRS+1]; /* stack enthalpies */ extern int entropies[NBPAIRS+1][NBPAIRS+1]; /* not used anymore */ extern int hairpin37[31]; extern int hairpindH[31]; extern int bulge37[31]; extern int bulgedH[31]; extern int internal_loop37[31]; extern int internal_loopdH[31]; extern int internal2_energy; extern int old_mismatch_37[NBPAIRS+1][5][5]; extern int mismatchI37[NBPAIRS+1][5][5]; /* interior loop mismatches */ extern int mismatchIdH[NBPAIRS+1][5][5]; /* interior loop mismatches */ extern int mismatch1nI37[NBPAIRS+1][5][5]; /* interior loop mismatches */ extern int mismatch23I37[NBPAIRS+1][5][5]; /* interior loop mismatches */ extern int mismatch1nIdH[NBPAIRS+1][5][5]; /* interior loop mismatches */ extern int mismatch23IdH[NBPAIRS+1][5][5]; /* interior loop mismatches */ extern int mismatchH37[NBPAIRS+1][5][5]; /* same for hairpins */ extern int mismatchM37[NBPAIRS+1][5][5]; /* same for multiloops */ extern int mismatchHdH[NBPAIRS+1][5][5]; /* same for hairpins */ extern int mismatchMdH[NBPAIRS+1][5][5]; /* same for multiloops */ extern int mismatchExt37[NBPAIRS+1][5][5]; extern int mismatchExtdH[NBPAIRS+1][5][5]; extern int dangle5_37[NBPAIRS+1][5]; /* 5' dangle exterior of pair */ extern int dangle3_37[NBPAIRS+1][5]; /* 3' dangle */ extern int dangle3_dH[NBPAIRS+1][5]; /* corresponding enthalpies */ extern int dangle5_dH[NBPAIRS+1][5]; extern int int11_37[NBPAIRS+1][NBPAIRS+1][5][5]; /* 1x1 interior loops */ extern int int11_dH[NBPAIRS+1][NBPAIRS+1][5][5]; extern int int21_37[NBPAIRS+1][NBPAIRS+1][5][5][5]; /* 2x1 interior loops */ extern int int21_dH[NBPAIRS+1][NBPAIRS+1][5][5][5]; extern int int22_37[NBPAIRS+1][NBPAIRS+1][5][5][5][5]; /* 2x2 interior loops */ extern int int22_dH[NBPAIRS+1][NBPAIRS+1][5][5][5][5]; /* constants for linearly destabilizing contributions for multi-loops F = ML_closing + ML_intern*(k-1) + ML_BASE*u */ extern int ML_BASE37; extern int ML_BASEdH; extern int ML_closing37; extern int ML_closingdH; extern int ML_intern37; extern int ML_interndH; extern int TripleC37; extern int TripleCdH; extern int MultipleCA37; extern int MultipleCAdH; extern int MultipleCB37; extern int MultipleCBdH; /* Ninio-correction for asymmetric internal loops with branches n1 and n2 */ /* ninio_energy = min{max_ninio, |n1-n2|*F_ninio[min{4.0, n1, n2}] } */ extern int MAX_NINIO; /* maximum correction */ extern int ninio37; extern int niniodH; /* penalty for helices terminated by AU (actually not GC) */ extern int TerminalAU37; extern int TerminalAUdH; /* penalty for forming bi-molecular duplex */ extern int DuplexInit37; extern int DuplexInitdH; /* stabilizing contribution due to special hairpins of size 4 (tetraloops) */ extern char Tetraloops[]; /* string containing the special tetraloops */ extern int Tetraloop37[]; /* Bonus energy for special tetraloops */ extern int TetraloopdH[]; extern char Triloops[]; /* string containing the special triloops */ extern int Triloop37[]; /* Bonus energy for special Triloops */ extern int TriloopdH[]; /* Bonus energy for special Triloops */ extern char Hexaloops[]; /* string containing the special triloops */ extern int Hexaloop37[]; /* Bonus energy for special Triloops */ extern int HexaloopdH[]; /* Bonus energy for special Triloops */ extern int GQuadAlpha37; extern int GQuadAlphadH; extern int GQuadBeta37; extern int GQuadBetadH; extern double Tmeasure; /* temperature of param measurements */ #endif