#include #include #include float vrna_fold_temperature( const char *string, char *structure, double temperature) { float mfe; vrna_fold_compound_t *vc; vrna_md_t md; vrna_md_set_default(&md); md.temperature = temperature; vc = vrna_fold_compound(string, &md, 0); mfe = vrna_mfe(vc, structure); vrna_fold_compound_free(vc); return mfe; } float vrna_cofold_temperature( const char *seq, char *structure, double temperature) { float mfe; vrna_fold_compound_t *vc; vrna_md_t md; vrna_md_set_default(&md); md.temperature = temperature; md.min_loop_size = 0; /* set min loop length to 0 */ /* get compound structure */ vc = vrna_fold_compound(seq, &md, 0); mfe = vrna_mfe_dimer(vc, structure); vrna_fold_compound_free(vc); return mfe; }