PMID- 12492297
OWN - NLM
STAT- MEDLINE
DCOM- 20030114
LR  - 20190910
IS  - 0735-7044 (Print)
IS  - 0735-7044 (Linking)
VI  - 116
IP  - 6
DP  - 2002 Dec
TI  - Organizing and activating effects of sex hormones in homosexual transsexuals.
PG  - 982-8
AB  - The cause of transsexualism remains unclear. The hypothesis that atypical 
      prenatal hormone exposure could be a factor in the development of transsexualism 
      was examined by establishing whether an atypical pattern of cognitive functioning 
      was present in homosexual transsexuals. Possible activating effects of sex 
      hormones as a result of cross-sex hormone treatment were also studied. 
      Female-to-male and male-to-female transsexuals were compared with female and male 
      controls with respect to spatial ability before and after treatment. The data 
      were consistent with an organizing effect, but there was no evidence of an 
      activating effect. Homosexual transsexuals, who prior to hormone treatment scored 
      in the direction of the opposite sex, may have reached a ceiling in performance 
      and therefore do not benefit from activating hormonal effects.
FAU - van Goozen, Stephanie H M
AU  - van Goozen SH
AD  - Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, 
      The Netherlands. shmv2@cam.ac.uk
FAU - Slabbekoorn, Ditte
AU  - Slabbekoorn D
FAU - Gooren, Louis J G
AU  - Gooren LJ
FAU - Sanders, Geoff
AU  - Sanders G
FAU - Cohen-Kettenis, Peggy T
AU  - Cohen-Kettenis PT
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Behav Neurosci
JT  - Behavioral neuroscience
JID - 8302411
RN  - 0 (Gonadal Steroid Hormones)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Cognition/*physiology
MH  - Female
MH  - Gonadal Steroid Hormones/*pharmacology
MH  - Homosexuality/*psychology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pregnancy
MH  - *Prenatal Exposure Delayed Effects
MH  - Transsexualism/*physiopathology
EDAT- 2002/12/21 04:00
MHDA- 2003/01/15 04:00
CRDT- 2002/12/21 04:00
PHST- 2002/12/21 04:00 [pubmed]
PHST- 2003/01/15 04:00 [medline]
PHST- 2002/12/21 04:00 [entrez]
AID - 10.1037//0735-7044.116.6.982 [doi]
PST - ppublish
SO  - Behav Neurosci. 2002 Dec;116(6):982-8. doi: 10.1037//0735-7044.116.6.982.